Vigorous Osteoinductivity Observed in Crude Bone Morphogenetic Protein Stored for 25 Years after Extraction at Room Temperature

نویسندگان

چکیده

Bone morphogenetic protein (BMP) is the only cytokine that induces heterotopic new bone. BMP has been classified as a subfamily of TGF superfamily. The most important and essential aspect for clinical application replenishment reinforcement bone defects fragile areas with However, it difficult to ascertain long term results. In this study, we examined osteogenic potential in mouse femoral fascia crude extracted from bovine had stored at room temperature 25 years. results showed vigorous osteogenesis. This study demonstrates long-term stability BMP.

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ژورنال

عنوان ژورنال: Journal of Hard Tissue Biology

سال: 2022

ISSN: ['1880-828X', '1341-7649']

DOI: https://doi.org/10.2485/jhtb.31.253